Cardiovascular Proteomics Techniques

Definitive reference on studying proteome biomarkers through cardiovascular disease pathophysiology and applied mass spectrometry

Cardiovascular Proteomics Techniques explores the intersection of cardiovascular disease pathophysiology and applied mass spectrometry to study proteome biomarkers. Leading experts provide a comprehensive overview of the physiopathology of cardiovascular system diseases, along with insights into their etiology and pathogenesis through proteomics. The book features 18 chapters covering a range of topics, including mass spectrometry, proteomics, atherosclerosis, heart biology, cardiovascular diseases, experimental models, network analysis, international proteomic initiatives, clinical proteomics, and sex and gender proteomics.

Cardiovascular Proteomics Techniques also includes in-depth discussions on:

• Antibody-based technologies for multiplexed protein detection and quantification, and their complementary role to mass spectrometry-based protein profiling.
• New findings from proteomic analysis regarding the pathogenesis of atherosclerosis.
• Emerging insights into the pathobiology of acute coronary syndromes.
• Network medicine as a new paradigm for cardiovascular disease research and beyond, with potential applications in drug repurposing.
• Recent advances in cardiovascular plasma proteomics and the exploration of previously unexplored cardiac diseases, such as Takotsubo syndrome.

This book is ideal for researchers in mass spectrometry, proteomics, life sciences, and cardiovascular studies. Cardiovascular Proteomics Techniques aims to enhance clinicians’ understanding of cardiovascular issues and to stimulate future developments in proteomics for the diagnosis and treatment of cardiovascular diseases.